Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.33 |
| ▸ | AKR1C2 | P52895 | 1/20 | 0.32 |
| ▸ | TUBB1 | Q9H4B7 | 2/20 | 0.32 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | STAT3 | P40763 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
| ▸ | SLC16A3 | O15427 | 4/20 | 0.31 |
| ▸ | SLC16A1 | P53985 | 4/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29063281 | 0.90 | LMNA (0.34) | LMNAMAPK1HTTRAB9AKDM4E | |
| SCHEMBL30396708 | 0.88 | KDM1A (0.34) | LMNAMAPK1HTTRAB9AKDM1A | |
| SCHEMBL29062696 | 0.80 | MAPT (0.38) | LMNARAB9ASLC16A3SLC16A1KDM4E | |
| SCHEMBL21490371 | 0.80 | CYP1A1 (0.42) | MAPK1RAB9AKDM4EKMT2A | |
| SCHEMBL21490370 | 0.80 | CYP1A1 (0.42) | MAPK1RAB9AKDM4EKMT2A | |
| SCHEMBL28700331 | 0.80 | CYP1A1 (0.42) | MAPK1RAB9AKDM4EKMT2A | |
| SCHEMBL29015549 | 0.80 | MAPT (0.44) | LMNAHTTRAB9AKDM4EKMT2A | |
| SCHEMBL25764619 | 0.78 | SMN1; SMN2 (0.34) | LMNAHTTRAB9ATUBB1KDM4E | |
| SCHEMBL29062714 | 0.76 | TPMT (0.34) | AKR1C2KDM4EGAA | |
| SCHEMBL20604873 | 0.76 | ERN1 (0.40) | LMNAHTTKDM4EKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116096714-A | Antiviral compounds for the treatment of coronavirus, picornavirus and norovirus infections | 安力高医药股份有限公司 | 2023-05-09 | — | — | CN | disclosed |