⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL30453252 | 0.87 | PDGFRB (0.32) | — | |
| Trifluoroacetic Acid SCHEMBL29015411 | 0.87 | PDGFRB (0.32) | — | |
| SCHEMBL24252685 | 0.84 | PDGFRB (0.32) | — | |
| SCHEMBL26771178 | 0.83 | CTSA (0.30) | — | |
| SCHEMBL30451527 | 0.76 | SCN9A (0.31) | — | |
| SCHEMBL24252662 | 0.76 | SCN9A (0.31) | — | |
| SCHEMBL25213423 | 0.75 | — | — | |
| SCHEMBL26771147 | 0.75 | SCN9A (0.31) | — | |
| SCHEMBL24252659 | 0.74 | DHFR (0.31) | — | |
| SCHEMBL26771089 | 0.73 | DHFR (0.30) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |