Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DHFR | P00374 | 1/20 | 0.36 |
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.33 |
| ▸ | FAAH | O00519 | 2/20 | 0.31 |
| ▸ | GRM2 | Q14416 | 1/20 | 0.31 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30451491 | 1.00 | DHFR (0.36) | DHFRPDE10AFAAHGRM2LRRK2 | |
| SCHEMBL24252258 | 0.85 | PDE10A (0.34) | DHFRPDE10ALRRK2 | |
| SCHEMBL26771228 | 0.83 | PDE10A (0.35) | DHFRPDE10ALRRK2 | |
| SCHEMBL30467724 | 0.79 | PDE10A (0.35) | DHFRPDE10ALRRK2 | |
| SCHEMBL24252636 | 0.79 | PDE10A (0.35) | DHFRPDE10ALRRK2 | |
| SCHEMBL26771273 | 0.78 | PDE10A (0.34) | PDE10A | |
| SCHEMBL24252632 | 0.77 | PDE10A (0.33) | DHFRPDE10ALRRK2 | |
| SCHEMBL24252384 | 0.76 | PDE10A (0.32) | PDE10A | |
| SCHEMBL30467623 | 0.76 | PDE10A (0.32) | PDE10A | |
| SCHEMBL26771278 | 0.76 | LRRK2 (0.35) | DHFRPDE10ALRRK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116947903-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-10-27 | — | — | CN | disclosed |
| CN-116261564-A | Inhibitors of complement factors and uses thereof | 安尼艾克松股份有限公司 | 2023-06-13 | — | — | CN | disclosed |