Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DDB1 | Q16531 | 5/20 | 0.38 |
| ▸ | CRBN | Q96SW2 | 5/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.37 |
| ▸ | ELANE | P08246 | 1/20 | 0.36 |
| ▸ | NR1H2 | P55055 | 3/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | BUB1 | O43683 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | BCHE | P06276 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28688256 | 0.78 | ESR2 (0.41) | DDB1CRBNESR2ELANENR1H2 | |
| SCHEMBL22720838 | 0.75 | NR1H2 (0.41) | DDB1CRBNESR2ELANENR1H2 | |
| SCHEMBL1239873 | 0.71 | NR1H2 (0.39) | DDB1CRBNESR2ELANENR1H2 | |
| Acetic Acid SCHEMBL28215593 | 0.71 | SMN1; SMN2 (0.40) | DDB1CRBNESR2ELANENR1H2 | |
| SCHEMBL28831819 | 0.71 | ESR2 (0.40) | DDB1CRBNESR2ELANENR1H2 | |
| SCHEMBL17267601 | 0.69 | ESR2 (0.40) | DDB1CRBNESR2NR1H2MAPT | |
| SCHEMBL3505154 | 0.68 | ESR2 (0.45) | ESR2ELANENR1H2MAPK1USP2 | |
| SCHEMBL19128587 | 0.68 | ELANE (0.33) | DDB1CRBNESR2ELANENR1H2 | |
| SCHEMBL30213616 | 0.68 | KDM4E (0.42) | DDB1CRBNESR2ELANENR1H2 | |
| SCHEMBL31482816 | 0.68 | ESR2 (0.37) | ESR2ELANENR1H2MAPTMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118103369-A | Pyridolactam derivatives, preparation method and application thereof | 浙江海正药业股份有限公司 | 2024-05-28 | — | — | CN | disclosed |
| CN-113227068-B | GLP-1R agonists and uses thereof | 上海齐鲁锐格医药研发有限公司 | 2023-06-13 | — | — | CN | disclosed |
| WO-2023030478-A1 | PYRIDOLACTAM DERIVATIVE, AND PREPARATION METHOD THEREFOR AND USE THEREOF | 浙江海正药业股份有限公司 | 2023-03-09 | — | — | WO | disclosed |