SCHEMBL29016573

SCHEMBL29016573

CCS(=O)(=O)c1ccc(CNC(=O)c2ccc3nc(Cc4ccc(C(F)(F)F)cc4)n(C(C)C)c3c2)cc1

nearest known ligand 0.74

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
RORC P51449 20/20 0.74

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29016570 0.94 RORC (0.83) RORC
SCHEMBL30370139 0.94 RORC (0.83) RORC
SCHEMBL19360337 0.86 RORC (0.75) RORC
SCHEMBL29016606 0.86 RORC (0.62) RORC
SCHEMBL19360478 0.85 RORC (0.69) RORC
SCHEMBL21750497 0.85 RORC (1.00) RORC
SCHEMBL21750580 0.84 RORC (1.00) RORC
SCHEMBL19360477 0.84 RORC (0.69) RORC
SCHEMBL21750551 0.84 RORC (1.00) RORC
SCHEMBL19360483 0.84 RORC (0.87) RORC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108689942-B Nitrogen-containing bicyclic compound, and preparation method and application thereof 广东东阳光药业有限公司 2023-06-09 CN disclosed