Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 1/20 | 0.50 |
| ▸ | SCN4A | P35499 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 8/20 | 0.44 |
| ▸ | GAA | P10253 | 4/20 | 0.44 |
| ▸ | NPC1 | O15118 | 4/20 | 0.44 |
| ▸ | RAB9A | P51151 | 4/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.44 |
| ▸ | GLA | P06280 | 3/20 | 0.44 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.44 |
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 6/20 | 0.43 |
| ▸ | MEN1 | O00255 | 3/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HPGD | P15428 | 2/20 | 0.43 |
| ▸ | QPCT | Q16769 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 2/20 | 0.41 |
| ▸ | THRB | P10828 | 1/20 | 0.41 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30370232 | 1.00 | EPHX2 (0.50) | EPHX2SCN4AMAPTGAANPC1 | |
| SCHEMBL30370205 | 0.88 | EPHX2 (0.51) | EPHX2SCN4AMAPTGAANPC1 | |
| SCHEMBL29016598 | 0.88 | EPHX2 (0.51) | EPHX2SCN4AMAPTGAANPC1 | |
| SCHEMBL30370173 | 0.84 | EPHX2 (0.43) | EPHX2SCN4AMAPTNPC1RAB9A | |
| SCHEMBL29016655 | 0.84 | EPHX2 (0.43) | EPHX2SCN4AMAPTNPC1RAB9A | |
| SCHEMBL29016594 | 0.80 | MAOB (0.51) | EPHX2SCN4AMAPTGAANPC1 | |
| SCHEMBL17198993 | 0.78 | MAPT (0.74) | EPHX2SCN4AMAPTGAANPC1 | |
| SCHEMBL30370452 | 0.77 | EPHX2 (0.48) | EPHX2SCN4AMAPTGAANPC1 | |
| SCHEMBL29016692 | 0.77 | EPHX2 (0.48) | EPHX2SCN4AMAPTGAANPC1 | |
| SCHEMBL2628250 | 0.73 | UBE2T (0.57) | EPHX2MAPTGAANPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689942-B | Nitrogen-containing bicyclic compound, and preparation method and application thereof | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |