Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOB | P27338 | 6/20 | 0.51 |
| ▸ | NPC1 | O15118 | 5/20 | 0.49 |
| ▸ | RAB9A | P51151 | 5/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | SCN4A | P35499 | 2/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.43 |
| ▸ | PKM | P14618 | 2/20 | 0.43 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.42 |
| ▸ | GMNN | O75496 | 1/20 | 0.42 |
| ▸ | USP2 | O75604 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.42 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29016544 | 0.85 | NPC1 (0.49) | MAOBNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL30370205 | 0.81 | EPHX2 (0.51) | MAOBNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL29016598 | 0.81 | EPHX2 (0.51) | MAOBNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL29016643 | 0.80 | EPHX2 (0.50) | MAOBNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL30370232 | 0.80 | EPHX2 (0.50) | MAOBNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL29016552 | 0.76 | NPC1 (0.46) | NPC1RAB9ASMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL7541252 | 0.74 | NPC1 (0.77) | NPC1RAB9ASMN1; SMN2KMT2AEPHX2 | |
| SCHEMBL659302 | 0.74 | SMN1; SMN2 (0.56) | NPC1RAB9ASMN1; SMN2KMT2AL3MBTL1 | |
| SCHEMBL17198993 | 0.73 | MAPT (0.74) | NPC1RAB9ASMN1; SMN2KMT2ASCN4A | |
| SCHEMBL7544263 | 0.73 | NPC1 (0.63) | MAOBNPC1RAB9ASMN1; SMN2KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689942-B | Nitrogen-containing bicyclic compound, and preparation method and application thereof | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |