Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HK2 | P52789 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.32 |
| ▸ | GRIK1 | P39086 | 3/20 | 0.31 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.31 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.31 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.31 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.31 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.31 |
| ▸ | MMP1 | P03956 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6813522 | 0.84 | GLA (0.37) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL3460388 | 0.77 | — | — | |
| SCHEMBL17165762 | 0.73 | GRIK1 (0.52) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL17165763 | 0.73 | GRIK1 (0.52) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL6341738 | 0.71 | GRIK1 (0.53) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL6682947 | 0.71 | GRIK1 (0.53) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL6711088 | 0.66 | GRIK1 (0.34) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL27692290 | 0.64 | APOBEC3A (0.42) | — | |
| SCHEMBL3836552 | 0.63 | HK2 (0.44) | HK2 | |
| SCHEMBL4278203 | 0.62 | ESR2 (0.55) | HK2OPRM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-108689942-B | Nitrogen-containing bicyclic compound, and preparation method and application thereof | 广东东阳光药业有限公司 | 2023-06-09 | — | — | CN | disclosed |