Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIK1 | P39086 | 5/20 | 0.53 |
| ▸ | GRIA1 | P42261 | 1/20 | 0.50 |
| ▸ | GRIA2 | P42262 | 1/20 | 0.50 |
| ▸ | GRIA4 | P48058 | 1/20 | 0.50 |
| ▸ | GRIK3 | Q13003 | 1/20 | 0.50 |
| ▸ | GRIK5 | Q16478 | 1/20 | 0.50 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.39 |
| ▸ | INMT | O95050 | 1/20 | 0.33 |
| ▸ | GRIK2 | Q13002 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | ESR1 | P03372 | 1/20 | 0.31 |
| ▸ | PGR | P06401 | 1/20 | 0.31 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.31 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.31 |
| ▸ | AR | P10275 | 1/20 | 0.31 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.31 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.31 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.31 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6341738 | 1.00 | GRIK1 (0.53) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL17165762 | 0.98 | GRIK1 (0.52) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL17165763 | 0.93 | GRIK1 (0.52) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL3460388 | 0.88 | — | — | |
| SCHEMBL11444881 | 0.82 | GRIK1 (0.40) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL9813656 | 0.79 | GRIK1 (0.55) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL6656745 | 0.78 | GRIK1 (0.35) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| Butane SCHEMBL4661674 | 0.78 | GRIK1 (0.46) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL11226300 | 0.77 | GPR84 (0.45) | GRIK1GRIA1GRIA2GRIA4GRIK3 | |
| SCHEMBL6711088 | 0.75 | GRIK1 (0.34) | GRIK1GRIA1GRIA2GRIA4GRIK3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004054957-A2 | VALPROIC ACID ANALOGUES AND PHARMACEUTICAL COMPOSITIONS THEREOF | THE UNIVERSITY OF BRITISH COLUMBIA (CA) | 2004-07-01 | — | — | WO | disclosed |