Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRIA2 | P42262 | 2/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | GRIN1 | Q05586 | 3/20 | 0.33 |
| ▸ | GRIN2A | Q12879 | 3/20 | 0.33 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 2/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2900104 | 0.80 | GRIA2 (0.44) | GRIA2KDM4EL3MBTL1GRIN1GRIN2A | |
| SCHEMBL18160599 | 0.75 | GRIN1 (0.41) | GRIA2KDM4EL3MBTL1GRIN1GRIN2A | |
| SCHEMBL2900830 | 0.74 | GRIN1 (0.35) | KDM4EGRIN1GRIN2AMEN1KMT2A | |
| SCHEMBL2904058 | 0.73 | — | — | |
| SCHEMBL2903361 | 0.72 | GRIA2 (0.43) | GRIA2KDM4EL3MBTL1GRIN1GRIN2A | |
| SCHEMBL2161378 | 0.69 | GRIN2A (0.40) | GRIA2KDM4EL3MBTL1GRIN1GRIN2A | |
| SCHEMBL24041760 | 0.68 | HDAC3 (0.54) | GRIA2MEN1KMT2AALDH1A1MAPT | |
| SCHEMBL1835376 | 0.68 | GRIA2 (0.46) | GRIA2KDM4EL3MBTL1GRIN1GRIN2A | |
| SCHEMBL1831143 | 0.68 | KDM4E (0.39) | GRIA2KDM4EL3MBTL1GRIN1GRIN2A | |
| SCHEMBL1186949 | 0.68 | GRIA2 (0.40) | GRIA2KDM4EL3MBTL1GRIN1GRIN2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | BAYER CROPSCIENCE AG (DE) | 2010-12-02 | — | — | US | disclosed |
| EP-2236505-A1 | Acylated aminopyridines and pyridazines as insecticides | Bayer CropScience AG (DE) | 2010-10-06 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100305124-A1 | Acylated Aminopyridine and Aminopyridazine Insecticides | AAAS, DDT, QDPR | GRIA2 705/4885KDM4E 762/4885L3MBTL1 1263/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.