Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 18/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.54 |
| ▸ | BTK | Q06187 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017117 | 1.00 | GLS (0.59) | GLSKCNH2BTK | |
| SCHEMBL29017110 | 0.89 | GLS (0.57) | GLSKCNH2 | |
| SCHEMBL29017108 | 0.89 | GLS (0.57) | GLSKCNH2 | |
| SCHEMBL29017195 | 0.88 | GLS (0.57) | GLSKCNH2 | |
| SCHEMBL29017144 | 0.88 | GLS (0.59) | GLSKCNH2 | |
| SCHEMBL29017147 | 0.88 | KCNH2 (0.58) | GLSKCNH2 | |
| SCHEMBL29017140 | 0.87 | KCNH2 (0.58) | GLSKCNH2 | |
| SCHEMBL29017137 | 0.87 | KCNH2 (0.58) | GLSKCNH2 | |
| SCHEMBL29017163 | 0.87 | GLS (0.62) | GLSKCNH2 | |
| SCHEMBL29017160 | 0.85 | GLS (0.55) | GLSKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594683-B | Glutaminase GLS1 inhibitor and preparation method and application thereof | 杭州禹胜医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-115594683-A | Glutaminase GLS1 inhibitor and preparation method and application thereof | 杭州禹胜医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |