Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 18/20 | 0.61 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.59 |
| ▸ | TACR1 | P25103 | 1/20 | 0.59 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.59 |
| ▸ | HTR2B | P41595 | 1/20 | 0.59 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.59 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017180 | 1.00 | GLS (0.61) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL29017157 | 0.94 | GLS (0.63) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL29017148 | 0.94 | GLS (0.63) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL24831933 | 0.85 | GLS (0.65) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL30336987 | 0.83 | CCNA2 (0.52) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL29017136 | 0.83 | CCNA2 (0.52) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL29017123 | 0.83 | CCNA2 (0.52) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL31294123 | 0.82 | GLS (0.53) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL24223366 | 0.77 | GLS (0.67) | GLSSLC6A2TACR1OPRM1HTR2B | |
| SCHEMBL24223373 | 0.77 | GLS (0.67) | GLSSLC6A2TACR1OPRM1HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594683-B | Glutaminase GLS1 inhibitor and preparation method and application thereof | 杭州禹胜医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-115594683-A | Glutaminase GLS1 inhibitor and preparation method and application thereof | 杭州禹胜医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |