Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GLS | O94925 | 19/20 | 0.59 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017191 | 1.00 | GLS (0.59) | GLSKCNH2 | |
| SCHEMBL29017137 | 0.92 | KCNH2 (0.58) | GLSKCNH2 | |
| SCHEMBL29017140 | 0.92 | KCNH2 (0.58) | GLSKCNH2 | |
| SCHEMBL29017151 | 0.92 | GLS (0.60) | GLS | |
| SCHEMBL29017149 | 0.92 | GLS (0.60) | GLS | |
| SCHEMBL29017163 | 0.89 | GLS (0.62) | GLSKCNH2 | |
| SCHEMBL29017139 | 0.89 | GLS (0.51) | GLSKCNH2 | |
| SCHEMBL30337141 | 0.89 | GLS (0.51) | GLSKCNH2 | |
| SCHEMBL29017135 | 0.89 | GLS (0.51) | GLSKCNH2 | |
| SCHEMBL29017134 | 0.88 | GLS (0.54) | GLSKCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115594683-B | Glutaminase GLS1 inhibitor and preparation method and application thereof | 杭州禹胜医药科技有限公司 | 2023-06-16 | — | — | CN | disclosed |
| CN-115594683-A | Glutaminase GLS1 inhibitor and preparation method and application thereof | 杭州禹胜医药科技有限公司（CN） | 2023-01-13 | — | — | CN | disclosed |