Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | BTK | Q06187 | 13/20 | 0.40 |
| ▸ | AURKA | O14965 | 1/20 | 0.40 |
| ▸ | PDPK1 | O15530 | 1/20 | 0.40 |
| ▸ | AURKB | Q96GD4 | 1/20 | 0.40 |
| ▸ | JAK3 | P52333 | 6/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | LCK | P06239 | 3/20 | 0.37 |
| ▸ | EGFR | P00533 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29017688 | 0.92 | BTK (0.43) | KMT2ABTKAURKAPDPK1AURKB | |
| SCHEMBL29017652 | 0.90 | BTK (0.51) | BTKJAK3LCKEGFR | |
| SCHEMBL29017672 | 0.90 | CNR2 (0.47) | KMT2ABTKJAK3MEN1LCK | |
| SCHEMBL29637913 | 0.90 | CNR2 (0.47) | KMT2ABTKJAK3MEN1LCK | |
| SCHEMBL29017667 | 0.87 | AURKA (0.44) | KMT2ABTKAURKAPDPK1AURKB | |
| SCHEMBL29017648 | 0.86 | KMT2A (0.42) | KMT2ABTKAURKAPDPK1AURKB | |
| SCHEMBL29017784 | 0.85 | PPARD (0.45) | KMT2ABTKAURKAPDPK1AURKB | |
| SCHEMBL29637911 | 0.85 | PPARD (0.45) | KMT2ABTKAURKAPDPK1AURKB | |
| SCHEMBL29637917 | 0.83 | KMT2A (0.44) | KMT2ABTKAURKAPDPK1AURKB | |
| SCHEMBL29017671 | 0.83 | KMT2A (0.44) | KMT2ABTKAURKAPDPK1AURKB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114478478-B | N- (1- (6- (substituted phenyl) pyridazin-3-yl) piperidin-3-yl) amine/amide derivatives and process for preparing the same | 厦门大学 | 2023-06-13 | — | — | CN | disclosed |