Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 4/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | HPGD | P15428 | 2/20 | 0.33 |
| ▸ | BLM | P54132 | 1/20 | 0.33 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.33 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.33 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.33 |
| ▸ | ATG4B | Q9Y4P1 | 1/20 | 0.33 |
| ▸ | PPARD | Q03181 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5507858 | 0.79 | APP (0.61) | APPMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9146168 | 0.79 | APP (0.61) | APPMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5507856 | 0.79 | APP (0.61) | APPMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL19026480 | 0.76 | MAPT (0.49) | APPMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL28978993 | 0.72 | APP (0.46) | APPMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5100970 | 0.71 | APP (0.50) | APPMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL9434307 | 0.71 | APP (0.50) | APPMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL5100967 | 0.71 | APP (0.50) | APPMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL840229 | 0.70 | APP (0.55) | APPMAPTCYP3A4CYP2C9CYP2C19 | |
| SCHEMBL3888883 | 0.70 | APP (0.48) | APPMAPTCYP3A4CYP2C9CYP2C19 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114920753-B | 6-fluoro-dihydropyran [2,3-c ] pyrazole derivative and synthetic method and application thereof | 华南理工大学 | 2023-06-20 | — | — | CN | disclosed |