Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 7/20 | 0.50 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.42 |
| ▸ | CASR | P41180 | 2/20 | 0.41 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.40 |
| ▸ | CA1 | P00915 | 2/20 | 0.40 |
| ▸ | CA2 | P00918 | 2/20 | 0.40 |
| ▸ | CA7 | P43166 | 2/20 | 0.40 |
| ▸ | CA9 | Q16790 | 2/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.39 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.39 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978895 | 0.85 | TRPV1 (0.46) | TRPV1P2RX7EPHX2PDE10ACA1 | |
| SCHEMBL23979029 | 0.85 | TRPV1 (0.46) | TRPV1P2RX7EPHX2PDE10ACA1 | |
| SCHEMBL30279329 | 0.83 | EPHX2 (0.60) | EPHX2CA1CA2 | |
| SCHEMBL24804265 | 0.83 | EPHX2 (0.60) | EPHX2CA1CA2 | |
| SCHEMBL13585440 | 0.83 | EPHX2 (0.60) | EPHX2CA1CA2 | |
| SCHEMBL23978684 | 0.83 | EPHX2 (0.60) | EPHX2CA1CA2 | |
| SCHEMBL24803505 | 0.81 | TRPV1 (0.58) | TRPV1P2RX7EPHX2PDE10ACA12 | |
| SCHEMBL24804785 | 0.79 | TRPV1 (0.45) | TRPV1P2RX7EPHX2PDE10A | |
| SCHEMBL4015713 | 0.79 | TRPV1 (0.58) | TRPV1P2RX7EPHX2PDE10AMAPK1 | |
| SCHEMBL29019147 | 0.78 | TRPV1 (0.45) | TRPV1PDE10A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916176-A | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |