Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TRPV1 | Q8NER1 | 8/20 | 0.46 |
| ▸ | EPHX2 | P34913 | 4/20 | 0.45 |
| ▸ | LIPG | Q9Y5X9 | 1/20 | 0.45 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.40 |
| ▸ | PDE10A | Q9Y233 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23978895 | 1.00 | TRPV1 (0.46) | TRPV1EPHX2LIPGP2RX7PDE10A | |
| SCHEMBL26508355 | 0.89 | EPHX2 (0.45) | TRPV1EPHX2LIPGPDE10ACA1 | |
| SCHEMBL23978772 | 0.88 | EPHX2 (0.58) | EPHX2LIPG | |
| SCHEMBL30083826 | 0.88 | EPHX2 (0.58) | EPHX2LIPG | |
| SCHEMBL30083831 | 0.88 | EPHX2 (0.58) | EPHX2LIPG | |
| SCHEMBL23978767 | 0.88 | EPHX2 (0.58) | EPHX2LIPG | |
| SCHEMBL24803485 | 0.88 | EPHX2 (0.58) | EPHX2LIPG | |
| SCHEMBL24804785 | 0.85 | TRPV1 (0.45) | TRPV1EPHX2LIPGP2RX7PDE10A | |
| SCHEMBL29019137 | 0.85 | TRPV1 (0.50) | TRPV1EPHX2P2RX7PDE10ACA1 | |
| SCHEMBL23978896 | 0.82 | CACNA1B (0.47) | TRPV1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021222789-A1 | INHIBITORS OF ALPHA 2 BETA 1 INTEGRIN AND METHODS OF USE THEREOF | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2021-11-04 | — | — | WO | disclosed |