Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 5/20 | 0.53 |
| ▸ | PPARG | P37231 | 4/20 | 0.53 |
| ▸ | ACE | P12821 | 1/20 | 0.52 |
| ▸ | CTSS | P25774 | 7/20 | 0.51 |
| ▸ | CTSK | P43235 | 6/20 | 0.51 |
| ▸ | CTSB | P07858 | 3/20 | 0.51 |
| ▸ | CTSL | P07711 | 2/20 | 0.51 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | ATM | Q13315 | 1/20 | 0.47 |
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | AKT1 | P31749 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29019158 | 1.00 | PPARA (0.53) | PPARAPPARGACECTSSCTSK | |
| SCHEMBL24803336 | 0.89 | SYK (0.52) | PPARAPPARGCTSSCTSKCTSB | |
| SCHEMBL23978700 | 0.89 | SYK (0.52) | PPARAPPARGCTSSCTSKCTSB | |
| SCHEMBL556571 | 0.81 | PPARA (0.57) | PPARAPPARGACECTSSCTSK | |
| SCHEMBL26932496 | 0.81 | PPARA (0.57) | PPARAPPARGACECTSSCTSK | |
| SCHEMBL29866102 | 0.81 | PPARA (0.57) | PPARAPPARGACECTSSCTSK | |
| SCHEMBL23978843 | 0.80 | CTSL (0.55) | CTSSCTSBCTSLAKT1 | |
| SCHEMBL4254558 | 0.80 | CTSL (0.57) | CTSSCTSBCTSLAKT1 | |
| SCHEMBL23978751 | 0.80 | NPC1 (0.51) | — | |
| SCHEMBL606625 | 0.80 | SYK (0.65) | PPARAPPARGACECTSSCTSK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916176-A | Inhibitors of alpha 2 beta 1 integrin and methods of use thereof | 加利福尼亚大学董事会 | 2023-04-04 | — | — | CN | disclosed |