Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 13/20 | 0.62 |
| ▸ | MGLL | Q99685 | 1/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 6/20 | 0.47 |
| ▸ | PTGDR | Q13258 | 2/20 | 0.47 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.46 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29019375 | 0.93 | PTGIR (0.69) | PTGIRMGLLPTGDR | |
| SCHEMBL23853931 | 0.87 | PTGIR (0.73) | PTGIRCHRM3PTGDRCHRM2CHRM1 | |
| SCHEMBL29019412 | 0.87 | PTGIR (0.73) | PTGIRMGLLCHRM3PTGDRCHRM2 | |
| SCHEMBL23851986 | 0.87 | PTGIR (0.73) | PTGIRCHRM3PTGDRCHRM2CHRM1 | |
| SCHEMBL29019410 | 0.87 | PTGIR (0.73) | PTGIRCHRM3PTGDRCHRM2CHRM1 | |
| SCHEMBL29019417 | 0.87 | PTGIR (0.64) | PTGIRMGLLCHRM3PTGDRCHRM2 | |
| SCHEMBL23851382 | 0.86 | PTGIR (0.68) | PTGIRMGLLPTGDR | |
| SCHEMBL29019408 | 0.86 | PTGIR (0.68) | PTGIRMGLLPTGDR | |
| SCHEMBL29019403 | 0.86 | PTGIR (0.68) | PTGIRMGLLCHRM3PTGDRCHRM2 | |
| SCHEMBL29019390 | 0.85 | PTGIR (0.67) | PTGIRMGLLCHRM3PTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003123-B | Modulators of the PGI2 receptor for the treatment of prostacyclin (PGI 2) receptor related disorders | 艾尼纳制药公司 | 2023-06-23 | — | — | CN | disclosed |