Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 15/20 | 0.73 |
| ▸ | PTGDR | Q13258 | 5/20 | 0.56 |
| ▸ | PTGER1 | P34995 | 1/20 | 0.56 |
| ▸ | PTGER4 | P35408 | 1/20 | 0.56 |
| ▸ | PTGER3 | P43115 | 1/20 | 0.56 |
| ▸ | PTGER2 | P43116 | 1/20 | 0.56 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.48 |
| ▸ | CHRM1 | P11229 | 2/20 | 0.48 |
| ▸ | CHRM3 | P20309 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 2/20 | 0.47 |
| ▸ | ACHE | P22303 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23851986 | 1.00 | PTGIR (0.73) | PTGIRPTGDRPTGER1PTGER4PTGER3 | |
| SCHEMBL23853931 | 1.00 | PTGIR (0.73) | PTGIRPTGDRPTGER1PTGER4PTGER3 | |
| SCHEMBL1118836 | 0.96 | PTGIR (0.79) | PTGIRPTGDRPTGER1PTGER4PTGER3 | |
| SCHEMBL1118834 | 0.96 | PTGIR (0.79) | PTGIRPTGDRPTGER1PTGER4PTGER3 | |
| SCHEMBL29019403 | 0.89 | PTGIR (0.68) | PTGIRPTGDRPTGER1PTGER4PTGER3 | |
| SCHEMBL29019417 | 0.88 | PTGIR (0.64) | PTGIRPTGDRCHRM2CHRM1CHRM3 | |
| SCHEMBL29019412 | 0.88 | PTGIR (0.73) | PTGIRPTGDRPTGER4PTGER3PTGER2 | |
| SCHEMBL29019401 | 0.87 | PTGIR (0.62) | PTGIRPTGDRCHRM2CHRM1CHRM3 | |
| SCHEMBL29019378 | 0.87 | PTGIR (0.62) | PTGIRPTGDRPTGER1PTGER4PTGER3 | |
| SCHEMBL29019390 | 0.86 | PTGIR (0.67) | PTGIRPTGDRPTGER4PTGER3PTGER2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003123-B | Modulators of the PGI2 receptor for the treatment of prostacyclin (PGI 2) receptor related disorders | 艾尼纳制药公司 | 2023-06-23 | — | — | CN | disclosed |