Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGIR | P43119 | 13/20 | 0.60 |
| ▸ | PTGDR | Q13258 | 3/20 | 0.46 |
| ▸ | CTPS1 | P17812 | 2/20 | 0.45 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.42 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.42 |
| ▸ | F11 | P03951 | 1/20 | 0.41 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29019418 | 0.88 | PTGIR (0.62) | PTGIRPTGDRF11 | |
| SCHEMBL29019387 | 0.88 | PTGIR (0.70) | PTGIRPTGDR | |
| SCHEMBL29019409 | 0.86 | PTGIR (0.65) | PTGIRPTGDR | |
| SCHEMBL29019388 | 0.86 | PTGIR (0.62) | PTGIRPTGDR | |
| SCHEMBL29019395 | 0.80 | PTGIR (0.67) | PTGIRPTGDR | |
| SCHEMBL23851986 | 0.79 | PTGIR (0.73) | PTGIRPTGDR | |
| SCHEMBL29019412 | 0.79 | PTGIR (0.73) | PTGIRPTGDR | |
| SCHEMBL29019410 | 0.79 | PTGIR (0.73) | PTGIRPTGDR | |
| SCHEMBL23853931 | 0.79 | PTGIR (0.73) | PTGIRPTGDR | |
| SCHEMBL29019375 | 0.79 | PTGIR (0.69) | PTGIRPTGDR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110003123-B | Modulators of the PGI2 receptor for the treatment of prostacyclin (PGI 2) receptor related disorders | 艾尼纳制药公司 | 2023-06-23 | — | — | CN | disclosed |