SCHEMBL29019451

SCHEMBL29019451

CCC(=O)Oc1c(N)cccc1NC(=O)OC(C)(C)C

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RXFP1 Q9HBX9 1/20 0.41
HDAC1 Q13547 3/20 0.39
EPHX2 P34913 1/20 0.38
ACHE P22303 1/20 0.38
BRD9 Q9H8M2 1/20 0.38
HDAC3 O15379 2/20 0.38
HDAC2 Q92769 1/20 0.38
HDAC10 Q969S8 1/20 0.38
HDAC6 Q9UBN7 1/20 0.38
NCOR2 Q9Y618 1/20 0.38
RAB9A P51151 1/20 0.37
KMT2A Q03164 2/20 0.37
METAP1 P53582 1/20 0.37
LMNA P02545 1/20 0.36
POLB P06746 1/20 0.36
KDM4E B2RXH2 1/20 0.36
ALDH1A1 P00352 1/20 0.36
GLA P06280 1/20 0.36
GAA P10253 1/20 0.36
MAPT P10636 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2499152 0.86 HSP90AA1 (0.41) RXFP1ACHEBRD9KMT2AMETAP1
SCHEMBL6651046 0.85 RXFP1 (0.39) RXFP1ACHEBRD9RAB9AKMT2A
SCHEMBL2149381 0.84 KMT2A (0.41) RXFP1EPHX2KMT2ALMNAKDM4E
SCHEMBL28875790 0.84 RXFP1 (0.38) RXFP1ACHEBRD9RAB9AKMT2A
SCHEMBL2078471 0.84 RXFP1 (0.38) RXFP1ACHEBRD9KMT2AMETAP1
SCHEMBL28875815 0.82 RXFP1 (0.38) RXFP1ACHEBRD9KMT2AMETAP1
SCHEMBL12475202 0.82 POLB (0.51) RXFP1EPHX2RAB9AKMT2ALMNA
SCHEMBL28820764 0.82 HSD17B10 (0.43) HDAC1ACHEHDAC3HDAC2RAB9A
SCHEMBL28556283 0.81 RXFP1 (0.37) RXFP1ACHEBRD9KMT2AMETAP1
SCHEMBL28546045 0.81 RXFP1 (0.37) RXFP1ACHEBRD9RAB9AKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110475785-B Peptide compound, method for producing same, composition for screening, and method for selecting peptide compound 富士胶片株式会社 2023-06-13 CN disclosed