Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.41 |
| ▸ | BRD4 | O60885 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 2/20 | 0.38 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.38 |
| ▸ | CTSS | P25774 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 1/20 | 0.38 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.38 |
| ▸ | PDK3 | Q15120 | 1/20 | 0.38 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.37 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28720031 | 0.90 | MTNR1B (0.40) | KMT2AL3MBTL1BRD4GAAALDH1A1 | |
| SCHEMBL21808583 | 0.87 | RXFP1 (0.39) | KMT2AGAAALDH1A1RXFP1EPHX2 | |
| SCHEMBL29103423 | 0.86 | L3MBTL1 (0.46) | KMT2AL3MBTL1GAAALDH1A1RXFP1 | |
| SCHEMBL1097144 | 0.85 | BRD4 (0.49) | KMT2AL3MBTL1BRD4SMN1; SMN2GAA | |
| SCHEMBL2499152 | 0.85 | HSP90AA1 (0.41) | KMT2ABRD4ALDH1A1RXFP1LMNA | |
| SCHEMBL28956936 | 0.84 | GAA (0.38) | BRD4SMN1; SMN2GAAALDH1A1PDK1 | |
| SCHEMBL15674183 | 0.84 | KCNQ4 (0.40) | KMT2AL3MBTL1ALDH1A1RXFP1EPHX2 | |
| SCHEMBL15689395 | 0.84 | PRMT5 (0.35) | SMN1; SMN2GAARXFP1EPHX2LMNA | |
| SCHEMBL6651046 | 0.84 | RXFP1 (0.39) | KMT2ABRD4ALDH1A1RXFP1LMNA | |
| SCHEMBL29019451 | 0.84 | RXFP1 (0.41) | KMT2AGAAALDH1A1RXFP1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110520413-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2023-02-17 | — | — | CN | disclosed |
| CN-108884058-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2022-04-29 | — | — | CN | disclosed |
| CN-109219596-B | Macrocyclic broad spectrum antibiotics | 阿奇克斯制药公司 | 2022-04-19 | — | — | CN | disclosed |
| CN-107848962-B | Urea derivative or pharmacologically acceptable salt thereof | 杏林制药株式会社 | 2021-04-09 | — | — | CN | disclosed |
| EP-2342194-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | Galderma Research & Development (FR) | 2011-07-13 | — | — | EP | disclosed |
| WO-2010052253-A1 | OXOAZETIDINE DERIVATIVES, PROCESS FOR THE PREPARATION THEREOF AND USE THEREOF IN HUMAN MEDICINE AND IN COSMETICS | GALDERMA RESEARCH & DEVELOPMENT (FR) | 2010-05-14 | — | — | WO | disclosed |
| EP-1140924-A1 | PIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-10-10 | — | — | EP | disclosed |
| WO-2000035915-A1 | PIPERAZINE DERIVATIVES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-06-22 | — | — | WO | disclosed |