SCHEMBL29019489

SCHEMBL29019489

CC(=O)c1cnc2cc(C(=O)O)nn2c1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 6/20 0.57
APOBEC3A P31941 4/20 0.50
LMNA P02545 3/20 0.50
APOBEC3G Q9HC16 2/20 0.50
ALDH1A1 P00352 6/20 0.41
TDP1 Q9NUW8 4/20 0.41
MAPT P10636 2/20 0.41
GAA P10253 2/20 0.41
RECQL P46063 1/20 0.40
HPGD P15428 3/20 0.39
ESR2 Q92731 3/20 0.39
TSHR P16473 1/20 0.39
MEN1 O00255 1/20 0.39
KMT2A Q03164 1/20 0.39
POLB P06746 6/20 0.38
RAB9A P51151 3/20 0.38
SMN1; SMN2 Q16637 2/20 0.38
HSD17B10 Q99714 1/20 0.38
NR4A1 P22736 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23728468 0.84 LMNA (0.66) KDM4EAPOBEC3ALMNAAPOBEC3GALDH1A1
SCHEMBL8214427 0.81 KDM4E (0.60) KDM4EAPOBEC3ALMNAAPOBEC3GALDH1A1
SCHEMBL21639018 0.80 LMNA (0.47) KDM4ELMNAALDH1A1TDP1GAA
SCHEMBL25941813 0.79 KDM4E (0.61) KDM4EAPOBEC3ALMNAAPOBEC3GALDH1A1
SCHEMBL12467159 0.78 KDM4E (0.60) KDM4EAPOBEC3ALMNAAPOBEC3GALDH1A1
SCHEMBL930189 0.78 KDM4E (0.60) KDM4EAPOBEC3ALMNAAPOBEC3GALDH1A1
SCHEMBL14307941 0.78 KDM4E (0.60) KDM4EAPOBEC3ALMNAAPOBEC3GALDH1A1
SCHEMBL1011158 0.78 TDP1 (0.63) KDM4EAPOBEC3ALMNAAPOBEC3GALDH1A1
SCHEMBL25097588 0.77 KDM4E (0.56) KDM4EAPOBEC3ALMNAAPOBEC3GALDH1A1
SCHEMBL21688705 0.77 LMNA (0.49) KDM4ELMNAALDH1A1TDP1MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-110475785-B Peptide compound, method for producing same, composition for screening, and method for selecting peptide compound 富士胶片株式会社 2023-06-13 CN disclosed