Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AURKA | O14965 | 2/20 | 0.46 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.44 |
| ▸ | MAPK10 | P53779 | 2/20 | 0.43 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.43 |
| ▸ | CCNA2 | P20248 | 3/20 | 0.43 |
| ▸ | CDK2 | P24941 | 3/20 | 0.43 |
| ▸ | CCNK | O75909 | 2/20 | 0.43 |
| ▸ | CCND3 | P30281 | 2/20 | 0.43 |
| ▸ | CDK9 | P50750 | 2/20 | 0.43 |
| ▸ | CDK6 | Q00534 | 2/20 | 0.43 |
| ▸ | BCL6 | P41182 | 1/20 | 0.43 |
| ▸ | LCK | P06239 | 1/20 | 0.42 |
| ▸ | LRRK2 | Q5S007 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | ALK | Q9UM73 | 1/20 | 0.41 |
| ▸ | MAPK13 | O15264 | 1/20 | 0.41 |
| ▸ | MAPK12 | P53778 | 1/20 | 0.41 |
| ▸ | MAPK11 | Q15759 | 1/20 | 0.41 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30394905 | 1.00 | AURKA (0.46) | AURKAPTK2MAPK10MAPK9CCNA2 | |
| SCHEMBL2062564 | 0.85 | IGF1R (0.54) | AURKACCNA2CDK2CCNKCCND3 | |
| SCHEMBL30184233 | 0.81 | ALK (0.44) | AURKAMAPK10MAPK9CCNA2CDK2 | |
| SCHEMBL30833698 | 0.81 | ULK1 (0.43) | AURKAMAPK10MAPK9CCNA2CDK2 | |
| SCHEMBL30394901 | 0.81 | CCNA2 (0.63) | CCNA2CDK2CCNKCCND3CDK9 | |
| SCHEMBL24752703 | 0.81 | ALK (0.44) | AURKAMAPK10MAPK9CCNA2CDK2 | |
| SCHEMBL28969585 | 0.81 | CDK2 (0.43) | AURKAMAPK10MAPK9CCNA2CDK2 | |
| SCHEMBL30833632 | 0.81 | BCL6 (0.50) | MAPK10MAPK9CCNA2CDK2CCNK | |
| SCHEMBL26161918 | 0.81 | CCNA2 (0.63) | CCNA2CDK2CCNKCCND3CDK9 | |
| SCHEMBL3340093 | 0.81 | BCL6 (0.50) | MAPK10MAPK9CCNA2CDK2CCNK |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-111620852-B | 5-chloro-pyrimidine-2, 4-diamine compound, and preparation method and application thereof | 镇江植生源农业科技有限公司 | 2023-05-09 | — | — | CN | disclosed |