SCHEMBL29020239

SCHEMBL29020239

CCCn1cccc1C(=O)OCc1ccccc1

nearest known ligand 0.57

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
RAB9A P51151 5/20 0.51
NPC1 O15118 2/20 0.51
ALDH1A1 P00352 7/20 0.49
TDP1 Q9NUW8 3/20 0.49
L3MBTL1 Q9Y468 3/20 0.49
MAPK1 P28482 2/20 0.49
TSHR P16473 2/20 0.49
CYP3A4 P08684 1/20 0.49
KMT2A Q03164 2/20 0.49
SLC6A2 P23975 1/20 0.49
SLC6A3 Q01959 1/20 0.49
LMNA P02545 1/20 0.45
TP53 P04637 1/20 0.44
NFKB1 P19838 1/20 0.44
NFKB2 Q00653 1/20 0.44
RELA Q04206 1/20 0.44
SMN1; SMN2 Q16637 1/20 0.44
MAPT P10636 2/20 0.43
HPGD P15428 1/20 0.43
GAA P10253 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29020275 0.92 ALDH1A1 (0.53) RAB9ANPC1ALDH1A1TDP1L3MBTL1
SCHEMBL29020291 0.91 ALDH1A1 (0.52) RAB9ANPC1ALDH1A1TDP1L3MBTL1
SCHEMBL31500283 0.88 TDP1 (0.51) RAB9ANPC1ALDH1A1TDP1L3MBTL1
SCHEMBL29020286 0.85 NPC1 (0.48) RAB9ANPC1ALDH1A1TDP1L3MBTL1
SCHEMBL29020281 0.84 TDP1 (0.53) RAB9ANPC1ALDH1A1TDP1L3MBTL1
SCHEMBL29225365 0.83 TSHR (0.46) RAB9ANPC1ALDH1A1TDP1TSHR
SCHEMBL25893353 0.82 TDP1 (0.51) RAB9ANPC1ALDH1A1TDP1L3MBTL1
SCHEMBL20201248 0.82 NPC1 (0.72) RAB9ANPC1ALDH1A1TDP1L3MBTL1
SCHEMBL11463498 0.79 NPC1 (0.46) RAB9ANPC1ALDH1A1TSHRNFKB1
SCHEMBL25263170 0.78 NPC1 (0.47) RAB9ANPC1ALDH1A1TDP1L3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-115093355-B Preparation method of pyrrole ester compound 河南农业大学 2024-06-04 CN disclosed
CN-115093355-A Preparation method of pyrrole ester compound 河南农业大学 2022-09-23 CN disclosed