Thiobenzoic Acid

Thiobenzoic Acid

SCHEMBL29020503

C=Cc1cccc(COC(=S)c2ccccc2)c1.CC(C)(OC(=S)c1ccccc1)c1ccc(Cl)cc1.OC(=S)c1ccccc1.OC(=S)c1ccccc1

nearest known ligand 0.33

Full drug profile on Sugi Atlas →

Predicted protein targets (top 11)

geneUniProtsupporting neighboursconfidence
MRGPRX4 Q96LA9 2/20 0.32
NPC1 O15118 2/20 0.31
RAB9A P51151 2/20 0.31
ALDH1A1 P00352 1/20 0.31
POLB P06746 1/20 0.31
ALOX12 P18054 1/20 0.31
HTT P42858 1/20 0.31
SMN1; SMN2 Q16637 1/20 0.31
HSP90AA1 P07900 1/20 0.31
HCAR2 Q8TDS4 1/20 0.30
GLA P06280 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Thiobenzoic Acid SCHEMBL164263 0.84 TDP1 (0.36) NPC1RAB9AALDH1A1SMN1; SMN2HCAR2
Thiobenzoic Acid SCHEMBL163805 0.79 ALDH1A1 (0.41) NPC1RAB9AALDH1A1POLBALOX12
Thiobenzoic Acid SCHEMBL1524465 0.75 ALDH1A1 (0.43) NPC1RAB9AALDH1A1POLB
Thiobenzoic Acid SCHEMBL28352009 0.73 ALDH1A1 (0.47) MRGPRX4NPC1RAB9AALDH1A1POLB
Thiobenzoic Acid SCHEMBL29060728 0.71 ALDH1A1 (0.51) NPC1RAB9AALDH1A1POLBALOX12
Thiobenzoic Acid SCHEMBL161426 0.71 CA12 (0.39) NPC1RAB9AALDH1A1HCAR2
Thiobenzoic Acid SCHEMBL164093 0.70 ALDH1A1 (0.47) ALDH1A1HTTHSP90AA1
Thiobenzoic Acid SCHEMBL15388584 0.69 ALDH1A1 (0.46) ALDH1A1HTTHSP90AA1
SCHEMBL30471624 0.68 TDP1 (0.32) MRGPRX4HTT
SCHEMBL29020501 0.68 TDP1 (0.32) MRGPRX4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116323785-A Rubber composition, sulfide, and vulcanized molded article 电化株式会社 2023-06-23 CN disclosed
CN-116323784-A Rubber composition, sulfide, and vulcanized molded article 电化株式会社 2023-06-23 CN disclosed