Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.56 |
| ▸ | PDE6D | O43924 | 2/20 | 0.51 |
| ▸ | LMNA | P02545 | 1/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.50 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.43 |
| ▸ | SSTR3 | P32745 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29020553 | 0.89 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL29020544 | 0.87 | KMT2A (0.54) | MEN1KMT2ASMN1; SMN2PDE6DRAB9A | |
| SCHEMBL29020542 | 0.84 | MEN1 (0.59) | MEN1KMT2ASMN1; SMN2PDE6DLMNA | |
| SCHEMBL29020517 | 0.82 | TSHR (0.75) | MEN1KMT2ASMN1; SMN2PDE6DLMNA | |
| SCHEMBL30498868 | 0.81 | MEN1 (0.56) | MEN1KMT2ASMN1; SMN2PDE6DLMNA | |
| SCHEMBL30498866 | 0.81 | MEN1 (0.58) | MEN1KMT2ASMN1; SMN2PDE6DLMNA | |
| SCHEMBL29020529 | 0.71 | MEN1 (0.62) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL4206360 | 0.70 | HDAC2 (0.58) | MEN1KMT2ASMN1; SMN2PDE6DLMNA | |
| SCHEMBL29020558 | 0.69 | TSHR (0.79) | MEN1KMT2ASMN1; SMN2LMNATSHR | |
| SCHEMBL6408118 | 0.69 | L3MBTL1 (0.67) | MEN1KMT2ASMN1; SMN2PDE6DLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-113402473-B | Thiotriazole compound, preparation method and application thereof | 四川省医学科学院·四川省人民医院 | 2023-06-23 | — | — | CN | disclosed |
| CN-113402473-A | Thiotriazole compound, preparation method and application thereof | 四川省医学科学院·四川省人民医院 | 2021-09-17 | — | — | CN | disclosed |