Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | MAPT | P10636 | 4/20 | 0.60 |
| ▸ | NPC1 | O15118 | 3/20 | 0.60 |
| ▸ | RAB9A | P51151 | 3/20 | 0.60 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.60 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.60 |
| ▸ | GLA | P06280 | 1/20 | 0.60 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.60 |
| ▸ | GPR55 | Q9Y2T6 | 1/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | HPGD | P15428 | 1/20 | 0.51 |
| ▸ | CASP1 | P29466 | 1/20 | 0.51 |
| ▸ | CASP7 | P55210 | 1/20 | 0.51 |
| ▸ | ATM | Q13315 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL50715 | 0.94 | KDM4E (0.66) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL29398625 | 0.94 | KDM4E (0.66) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| Hydrochloric Acid SCHEMBL3320794 | 0.92 | KDM4E (0.64) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL30464099 | 0.92 | KDM4E (0.64) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL29489796 | 0.92 | KDM4E (0.64) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL1686110 | 0.92 | KDM4E (0.64) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL30278644 | 0.92 | KDM4E (0.64) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL31275980 | 0.92 | KDM4E (0.69) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL347181 | 0.92 | KDM4E (0.64) | KDM4EMAPTNPC1RAB9AL3MBTL1 | |
| SCHEMBL29400645 | 0.92 | KDM4E (0.64) | KDM4EMAPTNPC1RAB9AL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116082411-A | Ir (III) complex with antitumor immune activity and preparation method and application thereof | 广东医科大学 | 2023-05-09 | — | — | CN | claimed |
| CN-116425804-B | Cyclometalated iridium complex with anti-inflammatory and anti-tumor activities and preparation method and application thereof | 东莞市人民医院 | 2023-09-29 | — | — | CN | disclosed |
| CN-116425804-A | Cyclometalated iridium complex with anti-inflammatory and anti-tumor activities and preparation method and application thereof | 东莞市人民医院 | 2023-07-14 | — | — | CN | disclosed |
| CN-116082411-A | Ir (III) complex with antitumor immune activity and preparation method and application thereof | 广东医科大学 | 2023-05-09 | — | — | CN | disclosed |