Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDC7 | O00311 | 3/20 | 0.51 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 4/20 | 0.45 |
| ▸ | FAAH | O00519 | 2/20 | 0.45 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | JMJD6 | Q6NYC1 | 2/20 | 0.42 |
| ▸ | JAK2 | O60674 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 2/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29492261 | 1.00 | CDC7 (0.51) | CDC7DBF4SMN1; SMN2POLBTDP1 | |
| SCHEMBL25330648 | 0.87 | CDC7 (0.52) | CDC7DBF4SMN1; SMN2FAAHMAPT | |
| SCHEMBL29492223 | 0.87 | CDC7 (0.52) | CDC7DBF4SMN1; SMN2FAAHMAPT | |
| SCHEMBL25331024 | 0.79 | SYK (0.57) | JAK2 | |
| SCHEMBL25328737 | 0.76 | ALPL (0.55) | CDC7DBF4SMN1; SMN2POLBMAPT | |
| SCHEMBL6335193 | 0.75 | SMN1; SMN2 (0.79) | SMN1; SMN2POLBTDP1FAAHMAPT | |
| SCHEMBL26639175 | 0.74 | SMN1; SMN2 (0.47) | SMN1; SMN2POLBTDP1FAAHMAPT | |
| SCHEMBL23582667 | 0.74 | CYP1A2 (0.60) | CDC7DBF4SMN1; SMN2POLBMAPT | |
| SCHEMBL8064364 | 0.73 | SMN1; SMN2 (0.47) | SMN1; SMN2POLBTDP1FAAHMAPT | |
| SCHEMBL25329077 | 0.72 | NPC1 (0.47) | SMN1; SMN2FAAHMAPTALDH1A1JMJD6 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116323595-A | Pyrazolyl-pyrimidine derivatives as kinase inhibitors | 内尔维亚诺医疗科学公司 | 2023-06-23 | — | — | CN | disclosed |