Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | POLB | P06746 | 2/20 | 0.68 |
| ▸ | ADRA2A | P08913 | 3/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | GAA | P10253 | 1/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.51 |
| ▸ | GPR84 | Q9NQS5 | 1/20 | 0.49 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | TYR | P14679 | 1/20 | 0.46 |
| ▸ | CNR2 | P34972 | 2/20 | 0.45 |
| ▸ | TSHR | P16473 | 1/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.40 |
| ▸ | MCOLN3 | Q8TDD5 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27229506 | 0.81 | POLB (0.67) | POLBADRA2AALDH1A1KDM4EMEN1 | |
| SCHEMBL21928103 | 0.81 | POLB (0.57) | POLBADRA2AALDH1A1KMT2ALMNA | |
| SCHEMBL11427185 | 0.81 | POLB (1.00) | POLBADRA2AALDH1A1KDM4EMEN1 | |
| SCHEMBL4767726 | 0.78 | CNR2 (0.57) | POLBADRA2AALDH1A1KDM4EMEN1 | |
| SCHEMBL12080834 | 0.77 | POLB (0.61) | POLBALDH1A1KDM4EMEN1KMT2A | |
| SCHEMBL10533316 | 0.75 | ALDH1A1 (0.49) | POLBADRA2AALDH1A1KDM4EMEN1 | |
| SCHEMBL12079683 | 0.73 | MAPT (0.56) | POLBADRA2AALDH1A1KDM4EMEN1 | |
| SCHEMBL19147985 | 0.73 | CNR2 (0.63) | ADRA2AALDH1A1KDM4ECNR2TDP1 | |
| SCHEMBL8174724 | 0.73 | ALDH1A1 (0.55) | ADRA2AALDH1A1KDM4EGAASMN1; SMN2 | |
| SCHEMBL4375863 | 0.71 | POLB (0.62) | POLBALDH1A1KDM4EMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116284019-A | Preparation method of medical intermediate furo [3,2-c ] pyridine-4 (5H) -ketone derivative | 安徽工业大学 | 2023-06-23 | — | — | CN | disclosed |