Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | NR1H2 | P55055 | 1/20 | 0.39 |
| ▸ | EPHA2 | P29317 | 4/20 | 0.38 |
| ▸ | MAPT | P10636 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | PDK1 | Q15118 | 3/20 | 0.38 |
| ▸ | ERBB2 | P04626 | 1/20 | 0.37 |
| ▸ | EPHB4 | P54760 | 1/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | THRB | P10828 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29022279 | 1.00 | USP2 (0.47) | USP2SMN1; SMN2RECQLNR1H2EPHA2 | |
| SCHEMBL18259593 | 0.88 | USP2 (0.48) | USP2SMN1; SMN2RECQLNR1H2EPHA2 | |
| SCHEMBL18259594 | 0.88 | USP2 (0.48) | USP2SMN1; SMN2RECQLNR1H2EPHA2 | |
| SCHEMBL31479278 | 0.88 | USP2 (0.48) | USP2SMN1; SMN2RECQLNR1H2EPHA2 | |
| SCHEMBL19448345 | 0.86 | USP2 (0.49) | USP2SMN1; SMN2RECQLNR1H2EPHA2 | |
| SCHEMBL18689612 | 0.86 | USP2 (0.49) | USP2SMN1; SMN2RECQLNR1H2EPHA2 | |
| SCHEMBL19439155 | 0.86 | USP2 (0.49) | USP2SMN1; SMN2RECQLNR1H2EPHA2 | |
| SCHEMBL60605 | 0.86 | USP2 (0.51) | USP2SMN1; SMN2RECQLNR1H2EPHA2 | |
| SCHEMBL554849 | 0.86 | USP2 (0.51) | USP2SMN1; SMN2RECQLNR1H2EPHA2 | |
| SCHEMBL555079 | 0.86 | USP2 (0.51) | USP2SMN1; SMN2RECQLNR1H2EPHA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-107793409-B | Dihydropyrimidine compound and application thereof in medicine | 广东东阳光药业有限公司 | 2022-09-27 | — | — | CN | disclosed |