SCHEMBL60605

SCHEMBL60605

CC(C)(C)OC(=O)N1CCOC(CN)C1

nearest known ligand 0.51

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
USP2 O75604 1/20 0.51
SMN1; SMN2 Q16637 1/20 0.51
RECQL P46063 1/20 0.46
NR1H2 P55055 1/20 0.42
MAPT P10636 2/20 0.41
MEN1 O00255 1/20 0.41
ALDH1A1 P00352 1/20 0.41
KMT2A Q03164 1/20 0.41
PDK1 Q15118 4/20 0.41
EPHA2 P29317 4/20 0.40
KDM4E B2RXH2 1/20 0.39
THRB P10828 1/20 0.39
ERBB2 P04626 1/20 0.39
EPHB4 P54760 1/20 0.39
HPGD P15428 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL555079 1.00 USP2 (0.51) USP2SMN1; SMN2RECQLNR1H2MAPT
SCHEMBL554849 1.00 USP2 (0.51) USP2SMN1; SMN2RECQLNR1H2MAPT
Hydrochloric Acid SCHEMBL31601582 0.99 USP2 (0.50) USP2SMN1; SMN2RECQLNR1H2MAPT
Acetic Acid SCHEMBL31055697 0.96 USP2 (0.48) USP2SMN1; SMN2RECQLNR1H2MAPT
SCHEMBL8004062 0.92 MAPT (0.48) USP2SMN1; SMN2RECQLNR1H2MAPT
SCHEMBL13779825 0.92 MAPT (0.48) USP2SMN1; SMN2RECQLNR1H2MAPT
SCHEMBL15107826 0.92 MAPT (0.48) USP2SMN1; SMN2RECQLNR1H2MAPT
SCHEMBL19448345 0.89 USP2 (0.49) USP2SMN1; SMN2RECQLNR1H2MAPT
SCHEMBL18689612 0.89 USP2 (0.49) USP2SMN1; SMN2RECQLNR1H2MAPT
SCHEMBL19439155 0.89 USP2 (0.49) USP2SMN1; SMN2RECQLNR1H2MAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 420 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3886904-B1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS INC (US) 2026-04-22 EP disclosed
US-12606561-B2 Substituted pyrazolo[1,5-a][1,3,5]triazines as CDK inhibitors QURIENT CO., LTD. (KR) 2026-04-21 US disclosed
EP-4682148-A2 APOPTOSIS-INDUCING AGENTS FOR THE TREATMENT OF CANCER AND IMMUNE AND AUTOIMMUNE DISEASES AbbVie Ireland Unlimited Company (IE) 2026-01-21 EP disclosed
US-12428395-B2 Heterocyclic compounds as kinase inhibitor and uses thereof SPEROGENIX THERAPEUTICS LIMITED (CN) 2025-09-30 US disclosed
EP-4007757-B1 HETEROCYCLIC COMPOUNDS AS KINASE INHIBITOR AND USES THEREOF SPEROGENIX THERAPEUTICS LTD (HK) 2025-09-10 EP disclosed
WO-2025124586-A1 DEGRADABLE CATIONIC LIPID CONTAINING DISULFIDE BOND AND USE THEREOF 厦门赛诺邦格生物科技股份有限公司 2025-06-19 WO disclosed
EP-4558137-A2 CHROMANE AMIDINE MONOBACTAM COMPOUNDS FOR THE TREATMENT OF BACTERIAL INFECTIONS Merck Sharp & Dohme LLC (US) 2025-05-28 EP disclosed
US-20250161318-A1 SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT ABBVIE INC (US) 2025-05-22 US disclosed
US-20250163042-A1 IRAK DEGRADERS AND USES THEREOF KYMERA THERAPEUTICS, INC. 2025-05-22 US disclosed
EP-4545515-A1 BCL-2 INHIBITORS BeiGene Switzerland GmbH (CH) 2025-04-30 EP disclosed
WO-2002090355-A1 N-AROYL CYCLIC AMINES SMITHKLINE BEECHAM P.L.C. (GB) 2002-11-14 WO disclosed
WO-2002026723-A1 COMPOUNDS USEFUL IN THE TREATMENT OF INFLAMMATORY DISEASES GLAXO GROUP LIMITED (GB) 2002-04-04 WO disclosed
US-5763436-A ANTICOAGULANTS HOFFMANN-LA ROCHE INC. (US) 1998-06-09 US disclosed
US-5595999-A ANTICOAGULANTS HOFFMANN-LA ROCHE INC. (US) 1997-01-21 US disclosed
US-5583133-A ANTICOAGULANTS HOFFMANN-LA ROCHE INC. (US) 1996-12-10 US disclosed
US-5532232-A INHIBIT THROMBIN INDUCED PLATELET AGGREGATION; FIBRINOGEN ANTICOAGULANTS IN BLOOD HOFFMANN-LA ROCHE INC. (US) 1996-07-02 US disclosed
US-5393760-A Cardiovascular disorders, antitumor agents HOFFMANN-LA ROCHE INC. (US) 1995-02-28 US disclosed
EP-0468231-B1 Guanidins HOFFMANN LA ROCHE (CH) 1994-09-21 EP disclosed
US-5260307-A Inhibit thrombin-induced platlet aggregation and clotting of fibrogen in plasma HOFMANN-LA ROCHE INC. (US) 1993-11-09 US disclosed
EP-0468231-A2 Guanidins F. HOFFMANN-LA ROCHE AG (CH) 1992-01-29 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-12606561-B2 Substituted pyrazolo[1,5-a][1,3,5]triazines as CDK inhibitors CDK6, CDKL1, CDK3 USP2 2191/4885SMN1; SMN2 4257/4885RECQL 1698/4885
US-20250163042-A1 IRAK DEGRADERS AND USES THEREOF IRAK2, IRAK3, IRAK1 USP2 141/4885SMN1; SMN2 2647/4885RECQL 2866/4885
US-12428395-B2 Heterocyclic compounds as kinase inhibitor and uses thereof CHEK1, CHEK2, CHKA USP2 1464/4885SMN1; SMN2 3709/4885RECQL 729/4885
US-20250161318-A1 SOLID DISPERSIONS CONTAINING AN APOPTOSIS-INDUCING AGENT BCL2, BAX, BCL2L1 USP2 1360/4885SMN1; SMN2 318/4885RECQL 1243/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.