SCHEMBL29022360

SCHEMBL29022360

N#Cc1cnc(-n2ccc3ccccc32)nc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
CDC7 O00311 9/20 0.45
CYP19A1 P11511 1/20 0.43
CDK2 P24941 4/20 0.42
ROCK1 Q13464 1/20 0.42
BIRC5 O15392 1/20 0.40
ENPP3 O14638 1/20 0.39
PRKD3 O94806 1/20 0.39
PRKCG P05129 1/20 0.39
PRKCB P05771 1/20 0.39
PRKCA P17252 1/20 0.39
PRKACA P17612 1/20 0.39
PRKACG P22612 1/20 0.39
PRKACB P22694 1/20 0.39
PRKCH P24723 1/20 0.39
PRKCI P41743 1/20 0.39
PRKCE Q02156 1/20 0.39
PRKCQ Q04759 1/20 0.39
PRKCZ Q05513 1/20 0.39
PRKCD Q05655 1/20 0.39
PRKD1 Q15139 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28930283 0.81 CDC7 (0.53) CDC7CYP19A1CDK2ROCK1MAP3K14
SCHEMBL29975548 0.78 CDC7 (0.45) CDC7CDK2ROCK1BIRC5PRKD3
SCHEMBL28389224 0.78 CDC7 (0.47) CDC7CDK2ROCK1BIRC5PRKD3
SCHEMBL29388240 0.77 RPS6KA5 (0.60) CDC7CDK2ROCK1BIRC5PRKD3
SCHEMBL2590108 0.77 RPS6KA5 (0.60) CDC7CDK2ROCK1BIRC5PRKD3
SCHEMBL5610137 0.75 CYP19A1 (0.62) CDC7CYP19A1CDK2ROCK1BIRC5
SCHEMBL13052919 0.74 BIRC5 (0.59) CDC7CDK2ROCK1BIRC5PRKD3
SCHEMBL23559754 0.74 CDC7 (0.42) CDC7CDK2ROCK1BIRC5PRKD3
SCHEMBL28562388 0.73 CDC7 (0.60) CDC7CYP19A1CDK2ENPP3MAP3K14
SCHEMBL6298226 0.71 CDC7 (0.48) CDC7CYP19A1CDK2BIRC5ENPP3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116288422-A Method for realizing 2-position alkylation of indole by utilizing micro-channel photoelectrocatalysis technology and product 南京工业大学 2023-06-23 CN disclosed