SCHEMBL29023201

SCHEMBL29023201

c1ccc(-c2ccc3c(ccc4c(-c5ccccc5)cccc43)c2)cc1

nearest known ligand 0.51

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HSD17B1 P14061 5/20 0.51
HSD17B2 P37059 5/20 0.51
CA12 O43570 2/20 0.47
CA1 P00915 2/20 0.47
CA2 P00918 2/20 0.47
CA9 Q16790 2/20 0.47
ESR1 P03372 5/20 0.47
ESR2 Q92731 5/20 0.47
CYP1A2 P05177 3/20 0.46
CYP3A4 P08684 2/20 0.46
CYP2D6 P10635 2/20 0.46
CYP2C9 P11712 2/20 0.46
CYP2B6 P20813 2/20 0.46
CYP2C19 P33261 2/20 0.46
ALDH1A1 P00352 2/20 0.43
HPGD P15428 2/20 0.43
GPR84 Q9NQS5 2/20 0.43
KDM4E B2RXH2 1/20 0.43
MEN1 O00255 1/20 0.43
MAPT P10636 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25622548 0.89 HSD17B1 (0.43) HSD17B1HSD17B2CA12CA1CA2
SCHEMBL13505946 0.88 HPRT1 (0.58) CA12CA1CA2CA9CYP1A2
SCHEMBL598398 0.88 HSD17B1 (0.59) HSD17B1HSD17B2CA12CA1CA2
SCHEMBL3005121 0.88 ESR1 (0.56) HSD17B1HSD17B2ESR1ESR2CYP1A2
SCHEMBL26054911 0.86 CA12 (0.48) HSD17B1HSD17B2CA12CA1CA2
SCHEMBL2724557 0.85 ESR1 (0.58) HSD17B1HSD17B2ESR1ESR2CYP1A2
SCHEMBL30703158 0.85 ESR1 (0.58) HSD17B1HSD17B2ESR1ESR2CYP1A2
SCHEMBL1987912 0.85 ESR1 (0.58) HSD17B1HSD17B2ESR1ESR2CYP1A2
SCHEMBL26047231 0.85 CA12 (0.47) HSD17B1HSD17B2CA12CA1CA2
SCHEMBL26550598 0.85 CA12 (0.59) HSD17B1HSD17B2CA12CA1CA2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116348454-A Triazine compound, material for organic electroluminescent element, electron-transporting material for organic electroluminescent element, and organic electroluminescent element 东曹株式会社 2023-06-27 CN disclosed