Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FLT3 | P36888 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 7/20 | 0.62 |
| ▸ | CASP3 | P42574 | 1/20 | 0.62 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.62 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.62 |
| ▸ | HTT | P42858 | 1/20 | 0.59 |
| ▸ | NPC1 | O15118 | 5/20 | 0.59 |
| ▸ | RAB9A | P51151 | 4/20 | 0.59 |
| ▸ | MAPK1 | P28482 | 4/20 | 0.59 |
| ▸ | TSHR | P16473 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.54 |
| ▸ | TP53 | P04637 | 2/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.54 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.54 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.54 |
| ▸ | RELA | Q04206 | 1/20 | 0.54 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.54 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7347858 | 0.87 | FLT3 (0.69) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL25395645 | 0.84 | MAPT (0.67) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL30770835 | 0.84 | MAPT (0.69) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL10468198 | 0.84 | FLT3 (0.65) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL27512421 | 0.84 | FLT3 (0.65) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL3529069 | 0.84 | MAPT (0.69) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL31619040 | 0.82 | MAPT (0.63) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL28107976 | 0.82 | MAPT (0.77) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL28960618 | 0.81 | MAPT (0.67) | FLT3MAPTCASP3SENP7TDP1 | |
| SCHEMBL244107 | 0.80 | FLT3 (1.00) | FLT3MAPTCASP3SENP7NPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116348471-A | Tetrazole derivatives as TRPA1 inhibitors | 勃林格殷格翰国际有限公司 | 2023-06-27 | — | — | CN | disclosed |