Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | OR51E2 | Q9H255 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22511454 | 0.79 | POLB (0.37) | MEN1MAPTTSHRMAPK1KMT2A | |
| SCHEMBL20053987 | 0.78 | MAPT (0.32) | MEN1MAPTTSHRMAPK1KMT2A | |
| SCHEMBL12987161 | 0.77 | MAPT (0.54) | MEN1MAPTTSHRMAPK1KMT2A | |
| SCHEMBL12987167 | 0.77 | MAPT (0.54) | MEN1MAPTTSHRMAPK1KMT2A | |
| SCHEMBL12987162 | 0.77 | MAPT (0.54) | MEN1MAPTTSHRMAPK1KMT2A | |
| SCHEMBL7995514 | 0.75 | NPC1 (0.53) | MEN1MAPTTSHRMAPK1KMT2A | |
| SCHEMBL7995512 | 0.75 | NPC1 (0.53) | MEN1MAPTTSHRMAPK1KMT2A | |
| SCHEMBL28826687 | 0.74 | OR51E2 (0.33) | MEN1MAPTTSHRMAPK1KMT2A | |
| SCHEMBL4434068 | 0.72 | RAB9A (0.54) | MEN1MAPTTSHRMAPK1KMT2A | |
| SCHEMBL4434071 | 0.72 | RAB9A (0.54) | MEN1MAPTTSHRMAPK1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116134035-A | 3- (1H-imidazol-2-yl) -2,3,8 a-tetrahydroindol-5 (1H) -one derivatives useful as factor XIA inhibitors | 詹森药业有限公司 | 2023-05-16 | — | — | CN | disclosed |