Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 20/20 | 0.76 |
| ▸ | ITGAV | P06756 | 20/20 | 0.76 |
| ▸ | ITGB5 | P18084 | 13/20 | 0.62 |
| ▸ | ITGA2B | P08514 | 8/20 | 0.62 |
| ▸ | ITGB1 | P05556 | 2/20 | 0.54 |
| ▸ | ITGB6 | P18564 | 1/20 | 0.50 |
| ▸ | ITGB8 | P26012 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL548056 | 0.86 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGA2BITGB1 | |
| SCHEMBL2923664 | 0.86 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGA2BITGB1 | |
| SCHEMBL4245408 | 0.86 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGA2BITGB1 | |
| SCHEMBL2951622 | 0.80 | ITGB3 (0.65) | ITGB3ITGAVITGB5ITGA2BITGB1 | |
| SCHEMBL2905430 | 0.78 | ITGB3 (0.84) | ITGB3ITGAVITGB5ITGA2BITGB1 | |
| SCHEMBL2902283 | 0.78 | ITGB3 (0.86) | ITGB3ITGAVITGB5ITGA2BITGB1 | |
| SCHEMBL2928161 | 0.77 | ITGB3 (0.79) | ITGB3ITGAVITGB5ITGA2BITGB1 | |
| SCHEMBL2922491 | 0.77 | ITGB3 (0.82) | ITGB3ITGAVITGB5ITGA2BITGB1 | |
| SCHEMBL2954835 | 0.77 | ITGB3 (1.00) | ITGB3ITGAVITGB5ITGA2B | |
| SCHEMBL2901622 | 0.75 | ITGB3 (0.92) | ITGB3ITGAVITGB5ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2217569-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | Janssen Pharmaceutica N.V. (BE) | 2010-08-18 | — | — | EP | disclosed |
| WO-2009058314-A1 | ENANTIOSELECTIVE PROCESS FOR PREPARING A SUBSTITUTED ALKANOIC ACID | JANSSEN PHARMACEUTICA, N.V. (BE) | 2009-05-07 | — | — | WO | disclosed |