Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 6/20 | 0.80 |
| ▸ | RAB9A | P51151 | 5/20 | 0.80 |
| ▸ | HTT | P42858 | 1/20 | 0.80 |
| ▸ | TMPRSS4 | Q9NRS4 | 5/20 | 0.72 |
| ▸ | KDR | P35968 | 1/20 | 0.62 |
| ▸ | P2RX1 | P51575 | 5/20 | 0.60 |
| ▸ | KCNMA1 | Q12791 | 3/20 | 0.60 |
| ▸ | P2RX4 | Q99571 | 2/20 | 0.60 |
| ▸ | P2RX7 | Q99572 | 2/20 | 0.60 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.60 |
| ▸ | POLB | P06746 | 2/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | MAPT | P10636 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | CASP3 | P42574 | 1/20 | 0.54 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.54 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.54 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30503661 | 1.00 | NPC1 (0.80) | NPC1RAB9AHTTTMPRSS4KDR | |
| SCHEMBL30503656 | 0.91 | NPC1 (0.67) | NPC1RAB9AHTTTMPRSS4KDR | |
| SCHEMBL29024717 | 0.91 | NPC1 (0.67) | NPC1RAB9AHTTTMPRSS4KDR | |
| SCHEMBL30503637 | 0.88 | NPC1 (0.64) | NPC1RAB9AHTTTMPRSS4PABPC1 | |
| SCHEMBL29024742 | 0.88 | NPC1 (0.64) | NPC1RAB9AHTTTMPRSS4PABPC1 | |
| SCHEMBL29024923 | 0.87 | NPC1 (0.78) | NPC1RAB9AHTTTMPRSS4PABPC1 | |
| SCHEMBL30503665 | 0.87 | NPC1 (0.78) | NPC1RAB9AHTTTMPRSS4PABPC1 | |
| SCHEMBL29024752 | 0.87 | NPC1 (0.78) | NPC1RAB9AHTTTMPRSS4PABPC1 | |
| SCHEMBL30503666 | 0.87 | NPC1 (0.78) | NPC1RAB9AHTTTMPRSS4PABPC1 | |
| SCHEMBL17770404 | 0.86 | P2RX1 (0.68) | NPC1RAB9AHTTTMPRSS4P2RX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354879-A | Benzamide derivative and application thereof | 中国药科大学 | 2023-06-30 | — | — | CN | disclosed |