Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 9/20 | 0.78 |
| ▸ | RAB9A | P51151 | 8/20 | 0.78 |
| ▸ | HTT | P42858 | 1/20 | 0.78 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | PABPC1 | P11940 | 1/20 | 0.58 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | CRHBP | P24387 | 1/20 | 0.56 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.56 |
| ▸ | TMPRSS4 | Q9NRS4 | 1/20 | 0.55 |
| ▸ | BLK | P51451 | 1/20 | 0.54 |
| ▸ | BTK | Q06187 | 1/20 | 0.54 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.53 |
| ▸ | BRAF | P15056 | 2/20 | 0.53 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30503665 | 1.00 | NPC1 (0.78) | NPC1RAB9AHTTPOLBPABPC1 | |
| SCHEMBL30503661 | 0.87 | NPC1 (0.80) | NPC1RAB9AHTTPOLBPABPC1 | |
| SCHEMBL29024932 | 0.87 | NPC1 (0.80) | NPC1RAB9AHTTPOLBPABPC1 | |
| SCHEMBL29024923 | 0.86 | NPC1 (0.78) | NPC1RAB9AHTTPOLBPABPC1 | |
| SCHEMBL30503666 | 0.86 | NPC1 (0.78) | NPC1RAB9AHTTPOLBPABPC1 | |
| SCHEMBL29024734 | 0.85 | NPC1 (0.73) | NPC1RAB9AHTTPOLBPABPC1 | |
| SCHEMBL30503670 | 0.85 | NPC1 (0.73) | NPC1RAB9AHTTPOLBPABPC1 | |
| SCHEMBL30503659 | 0.79 | PABPC1 (0.74) | NPC1RAB9AHTTPOLBPABPC1 | |
| SCHEMBL29024922 | 0.79 | PABPC1 (0.74) | NPC1RAB9AHTTPOLBPABPC1 | |
| SCHEMBL5897048 | 0.79 | BRAF (0.71) | NPC1RAB9AHTTPOLBPABPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354879-A | Benzamide derivative and application thereof | 中国药科大学 | 2023-06-30 | — | — | CN | disclosed |