Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | TSHR | P16473 | 1/20 | 0.43 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.43 |
| ▸ | THPO | P40225 | 1/20 | 0.43 |
| ▸ | BLM | P54132 | 1/20 | 0.43 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | P4HTM | Q9NXG6 | 2/20 | 0.40 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30503685 | 1.00 | KDM4E (0.43) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL27850558 | 0.83 | P4HTM (0.37) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL15061458 | 0.81 | MEN1 (0.41) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL16545869 | 0.80 | TDP1 (0.50) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL3261360 | 0.80 | TRPM8 (0.38) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL29024951 | 0.76 | MLNR (0.41) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL30503675 | 0.76 | MLNR (0.41) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL15061460 | 0.76 | TSHR (0.37) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL14651299 | 0.75 | P4HTM (0.47) | KDM4EMEN1ALDH1A1LMNACYP1A2 | |
| SCHEMBL10272733 | 0.75 | MAPT (0.46) | KDM4EMEN1ALDH1A1LMNACYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116354894-A | Substituted piperazine compound and application thereof in medicines | 广东东阳光药业有限公司 | 2023-06-30 | — | — | CN | disclosed |