Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | THRB | P10828 | 1/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.34 |
| ▸ | RXRA | P19793 | 2/20 | 0.34 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.33 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 2/20 | 0.32 |
| ▸ | SCN9A | Q15858 | 2/20 | 0.32 |
| ▸ | LIPE | Q05469 | 2/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29025588 | 0.91 | KMT2A (0.41) | KMT2ATHRBL3MBTL1MAPK1MRGPRX4 | |
| SCHEMBL29025590 | 0.83 | SMN1; SMN2 (0.41) | KMT2AL3MBTL1MRGPRX4SMN1; SMN2HPGD | |
| SCHEMBL29025591 | 0.83 | KMT2A (0.41) | KMT2ATHRBL3MBTL1MAPK1MRGPRX4 | |
| SCHEMBL29025570 | 0.82 | SMN1; SMN2 (0.46) | KMT2ATHRBL3MBTL1MAPK1MRGPRX4 | |
| SCHEMBL29025578 | 0.81 | KMT2A (0.38) | KMT2ATHRBL3MBTL1MAPK1MRGPRX4 | |
| SCHEMBL7071031 | 0.79 | KMT2A (0.46) | KMT2ATHRBL3MBTL1MAPK1MRGPRX4 | |
| SCHEMBL29025587 | 0.79 | KMT2A (0.41) | KMT2ATHRBL3MBTL1MAPK1MRGPRX4 | |
| SCHEMBL6671794 | 0.77 | MRGPRX4 (0.49) | KMT2AL3MBTL1MAPK1MRGPRX4SMN1; SMN2 | |
| SCHEMBL7073751 | 0.77 | MRGPRX4 (0.47) | KMT2ATHRBL3MBTL1MAPK1MRGPRX4 | |
| SCHEMBL14142827 | 0.76 | KMT2A (0.39) | KMT2ATHRBL3MBTL1MAPK1MRGPRX4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-116178249-B | Ether derivative with insecticidal and acaricidal activities as well as preparation method and application thereof | 北京亦农生物科技有限公司 | 2024-02-09 | — | — | CN | disclosed |
| CN-116178249-A | Ether derivative with insecticidal and acaricidal activities as well as preparation method and application thereof | 北京亦农生物科技有限公司 | 2023-05-30 | — | — | CN | disclosed |