SCHEMBL7071031

SCHEMBL7071031

Oc1cc(Cl)c(OCCCOc2ccc(C(F)(F)F)cn2)c(Cl)c1

nearest known ligand 0.46

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
KMT2A Q03164 2/20 0.46
MRGPRX4 Q96LA9 1/20 0.44
L3MBTL1 Q9Y468 2/20 0.42
MAPK1 P28482 1/20 0.40
SMN1; SMN2 Q16637 2/20 0.39
TSHR P16473 1/20 0.39
RAB9A P51151 1/20 0.39
LMNA P02545 2/20 0.39
MEN1 O00255 1/20 0.39
POLB P06746 1/20 0.39
HPGD P15428 1/20 0.39
THRB P10828 1/20 0.38
GABRA5 P31644 1/20 0.37
RXRA P19793 2/20 0.37
GRIN1 Q05586 2/20 0.37
GRIN2B Q13224 2/20 0.37
LIPE Q05469 2/20 0.36
TDP1 Q9NUW8 1/20 0.36
MGLL Q99685 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7073751 0.97 MRGPRX4 (0.47) KMT2AMRGPRX4L3MBTL1MAPK1SMN1; SMN2
SCHEMBL7076311 0.96 MRGPRX4 (0.46) KMT2AMRGPRX4L3MBTL1MAPK1SMN1; SMN2
SCHEMBL7078746 0.96 MRGPRX4 (0.46) KMT2AMRGPRX4L3MBTL1MAPK1SMN1; SMN2
SCHEMBL7073314 0.96 KMT2A (0.47) KMT2AMRGPRX4L3MBTL1MAPK1SMN1; SMN2
SCHEMBL7073758 0.92 KMT2A (0.41) KMT2AMRGPRX4L3MBTL1MAPK1SMN1; SMN2
SCHEMBL4624147 0.92 KMT2A (0.41) KMT2AMRGPRX4L3MBTL1MAPK1SMN1; SMN2
SCHEMBL7072961 0.89 MRGPRX4 (0.43) KMT2AMRGPRX4L3MBTL1MAPK1SMN1; SMN2
SCHEMBL7071231 0.87 L3MBTL1 (0.48) KMT2AMRGPRX4L3MBTL1MAPK1SMN1; SMN2
SCHEMBL29025570 0.85 SMN1; SMN2 (0.46) KMT2AMRGPRX4L3MBTL1MAPK1SMN1; SMN2
SCHEMBL7078903 0.84 L3MBTL1 (0.48) KMT2AMRGPRX4L3MBTL1MAPK1SMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116178249-B Ether derivative with insecticidal and acaricidal activities as well as preparation method and application thereof 北京亦农生物科技有限公司 2024-02-09 CN claimed
CN-116178249-A Ether derivative with insecticidal and acaricidal activities as well as preparation method and application thereof 北京亦农生物科技有限公司 2023-05-30 CN claimed
EP-0785923-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-04-05 EP claimed
US-5922880-A CONTROLLING INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-13 US claimed
EP-0785923-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-07-30 EP claimed
WO-1996011909-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-25 WO claimed
CN-116178249-B Ether derivative with insecticidal and acaricidal activities as well as preparation method and application thereof 北京亦农生物科技有限公司 2024-02-09 CN disclosed
CN-116178249-A Ether derivative with insecticidal and acaricidal activities as well as preparation method and application thereof 北京亦农生物科技有限公司 2023-05-30 CN disclosed
US-6589914-B2 The dihalopropene compounds of the general formula (I) have excellent insecticidal/acaricidal activity, so that they are satisfactorily effective for the control of noxious insects, mites and ticks. SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2003-07-08 US disclosed
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED 2003-04-17 US disclosed
US-6376428-B1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2002-04-23 US disclosed
US-6268313-B1 CONTROLLING INSECTS, MITES, TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 2001-07-31 US disclosed
US-6071861-A FOR THE CONTROL OF NOXIOUS INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, INC. (JP) 2000-06-06 US disclosed
EP-0785923-B1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL CO (JP) 2000-04-05 EP disclosed
US-5922880-A CONTROLLING INSECTS, MITES AND TICKS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1999-07-13 US disclosed
EP-0785923-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY LIMITED (JP) 1997-07-30 EP disclosed
WO-1996011909-A1 DIHALOPROPENE COMPOUNDS, INSECTICIDAL/ACARICIDAL AGENTS CONTAINING SAME, AND INTERMEDIATES FOR THEIR PRODUCTION SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1996-04-25 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20030073847-A1 Dihalopropene compounds, insecticidal/acaricidal agents containing same, and intermediates for their production DDT, DDC, AADAC KMT2A 2833/4885MRGPRX4 1668/4885L3MBTL1 1034/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.