Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARA | Q07869 | 11/20 | 0.36 |
| ▸ | PPARD | Q03181 | 7/20 | 0.36 |
| ▸ | CNR1 | P21554 | 1/20 | 0.36 |
| ▸ | PPARG | P37231 | 2/20 | 0.35 |
| ▸ | KDM1A | O60341 | 2/20 | 0.35 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.34 |
| ▸ | AR | P10275 | 2/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29025836 | 1.00 | PPARA (0.36) | PPARAPPARDCNR1PPARGKDM1A | |
| SCHEMBL29025831 | 0.90 | JAK3 (0.41) | — | |
| SCHEMBL30478720 | 0.90 | JAK3 (0.41) | — | |
| SCHEMBL29025830 | 0.90 | JAK3 (0.41) | — | |
| SCHEMBL29025880 | 0.85 | NOTUM (0.45) | ALDH1A1 | |
| SCHEMBL29025877 | 0.85 | NOTUM (0.45) | ALDH1A1 | |
| SCHEMBL22076905 | 0.82 | DPP4 (0.38) | KDM1AARALDH1A1SMN1; SMN2 | |
| SCHEMBL22076903 | 0.82 | DPP4 (0.38) | KDM1AARALDH1A1SMN1; SMN2 | |
| SCHEMBL30478648 | 0.79 | NR1H2 (0.40) | ARALDH1A1 | |
| SCHEMBL29025850 | 0.76 | GFER (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422755-B | Nitrogen-containing heterocyclic compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-109422755-A | A kind of nitrogen-containing heterocycle compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2019-03-05 | — | — | CN | disclosed |