Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GFER | P55789 | 4/20 | 0.42 |
| ▸ | GAA | P10253 | 3/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | JAK3 | P52333 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29025846 | 1.00 | GFER (0.42) | GFERGAAPOLBJAK3KMT2A | |
| SCHEMBL22076907 | 0.91 | JAK3 (0.49) | GFERJAK3 | |
| SCHEMBL22076904 | 0.91 | JAK3 (0.49) | GFERJAK3 | |
| SCHEMBL29025882 | 0.88 | USP30 (0.42) | GFERGAAJAK3KMT2A | |
| SCHEMBL29025881 | 0.88 | USP30 (0.42) | GFERGAAJAK3KMT2A | |
| SCHEMBL22076896 | 0.76 | DPP4 (0.38) | — | |
| SCHEMBL22076898 | 0.76 | DPP4 (0.38) | — | |
| SCHEMBL29025836 | 0.76 | PPARA (0.36) | — | |
| SCHEMBL29025838 | 0.76 | PPARA (0.36) | — | |
| SCHEMBL29025845 | 0.75 | QDPR (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109422755-B | Nitrogen-containing heterocyclic compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2023-07-04 | — | — | CN | disclosed |
| CN-109422755-A | A kind of nitrogen-containing heterocycle compound, preparation method, intermediate, composition and application | 上海医药集团股份有限公司 | 2019-03-05 | — | — | CN | disclosed |