Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 2/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 2/20 | 0.48 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.48 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CASR | P41180 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | ANPEP | P15144 | 2/20 | 0.45 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.44 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.43 |
| ▸ | PPIA | P62937 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16321397 | 1.00 | EPHX2 (0.49) | EPHX2ALDH1A1MAPTL3MBTL1TP53 | |
| SCHEMBL16321396 | 1.00 | EPHX2 (0.49) | EPHX2ALDH1A1MAPTL3MBTL1TP53 | |
| SCHEMBL16321395 | 1.00 | EPHX2 (0.49) | EPHX2ALDH1A1MAPTL3MBTL1TP53 | |
| SCHEMBL16321398 | 1.00 | EPHX2 (0.49) | EPHX2ALDH1A1MAPTL3MBTL1TP53 | |
| SCHEMBL16356140 | 0.86 | MAPT (0.48) | EPHX2ALDH1A1MAPTL3MBTL1TP53 | |
| SCHEMBL6436940 | 0.82 | EPHX2 (0.68) | EPHX2ALDH1A1MAPTL3MBTL1CASR | |
| SCHEMBL17232942 | 0.79 | GPR139 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL17232940 | 0.79 | GPR139 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL17232943 | 0.79 | GPR139 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2TDP1 | |
| SCHEMBL17232941 | 0.79 | GPR139 (0.50) | ALDH1A1MEN1KMT2ASMN1; SMN2TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-109384729-B | Pyrimidinedione compounds for cardiac disorders | 迈奥卡迪亚公司 | 2023-06-30 | — | — | CN | disclosed |