Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.43 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.43 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
| ▸ | BRD4 | O60885 | 1/20 | 0.39 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.39 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.38 |
| ▸ | RORC | P51449 | 1/20 | 0.38 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30288171 | 1.00 | LMNA (0.43) | LMNAAGTR1AGTR2ALDH1A1KDM4E | |
| SCHEMBL15129596 | 0.86 | MAPT (0.43) | LMNAAGTR1AGTR2ALDH1A1KDM4E | |
| SCHEMBL13044544 | 0.80 | KMT2A (0.44) | LMNAALDH1A1KDM4ETP53HPGD | |
| SCHEMBL10249906 | 0.78 | TSHR (0.47) | ALDH1A1TSHRMEN1KMT2ANLRP3 | |
| SCHEMBL6181763 | 0.78 | MEN1 (0.46) | LMNAALDH1A1KDM4ETP53HPGD | |
| SCHEMBL5929583 | 0.78 | SMN1; SMN2 (0.56) | LMNAALDH1A1KDM4ETP53HPGD | |
| SCHEMBL313449 | 0.78 | SMN1; SMN2 (0.56) | LMNAALDH1A1KDM4ETP53HPGD | |
| SCHEMBL17681956 | 0.77 | LMNA (0.41) | LMNAALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL28336015 | 0.77 | LMNA (0.41) | LMNAALDH1A1KDM4EHPGDHSD17B10 | |
| SCHEMBL17681986 | 0.77 | LMNA (0.41) | LMNAALDH1A1KDM4EHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115968372-A | Radioprotective and chemoprotective compounds | 通尼克斯医药有限公司 | 2023-04-14 | — | — | CN | disclosed |