Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | DUSP3 | P51452 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | DGKA | P23743 | 1/20 | 0.36 |
| ▸ | FAAH | O00519 | 4/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | USP2 | O75604 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL44490 | 0.89 | LMNA (0.48) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL2904697 | 0.89 | LMNA (0.48) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL2904704 | 0.89 | LMNA (0.48) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Glycerin SCHEMBL28991424 | 0.86 | LMNA (0.47) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Bicarbonate SCHEMBL27957894 | 0.84 | LMNA (0.46) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL21063352 | 0.83 | LMNA (0.42) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Alcohol SCHEMBL20504373 | 0.82 | LMNA (0.53) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Allyl Alcohol SCHEMBL27836124 | 0.81 | LMNA (0.41) | LMNAKDM4EDUSP3MEN1KMT2A | |
| SCHEMBL4337039 | 0.79 | LMNA (0.46) | LMNAKDM4EDUSP3MEN1KMT2A | |
| Acrylic Acid SCHEMBL23581831 | 0.79 | LMNA (0.40) | LMNAKDM4EDUSP3MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118304295-A | Pharmaceutical composition of endothelin A (ETA) receptor antagonist compound and application thereof | 深圳信立泰药业股份有限公司 | 2024-07-09 | — | — | CN | disclosed |
| CN-117447453-A | Pharmaceutically acceptable salt crystal forms of endothelin A (ETA) receptor antagonist compounds and preparation method thereof | 深圳信立泰药业股份有限公司 | 2024-01-26 | — | — | CN | disclosed |
| CN-116194449-A | Endothelin A (ETA) receptor antagonist compound and preparation method and medical application thereof | 深圳信立泰药业股份有限公司 | 2023-05-30 | — | — | CN | disclosed |