SCHEMBL29026181

SCHEMBL29026181

CC(C)(C)[Si](OCCOCCOCCN)(c1ccccc1)c1ccccc1

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
SMN1; SMN2 Q16637 2/20 0.40
SMYD2 Q9NRG4 3/20 0.37
CYP3A4 P08684 2/20 0.37
HTT P42858 1/20 0.37
KIF11 P52732 1/20 0.36
KDM4E B2RXH2 2/20 0.35
TAAR1 Q96RJ0 2/20 0.35
MAPK1 P28482 2/20 0.33
TP53 P04637 1/20 0.33
RAB9A P51151 1/20 0.33
MEN1 O00255 1/20 0.33
TRPM2 O94759 1/20 0.33
ALDH1A1 P00352 1/20 0.33
CYP1A2 P05177 1/20 0.33
THRB P10828 1/20 0.33
HPGD P15428 1/20 0.33
ALOX15 P16050 1/20 0.33
TSHR P16473 1/20 0.33
ALOX12 P18054 1/20 0.33
KMT2A Q03164 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL30426193 1.00 SMN1; SMN2 (0.40) SMN1; SMN2SMYD2CYP3A4HTTKIF11
SCHEMBL927307 1.00 SMN1; SMN2 (0.40) SMN1; SMN2SMYD2CYP3A4HTTKIF11
SCHEMBL15679439 1.00 SMN1; SMN2 (0.40) SMN1; SMN2SMYD2CYP3A4HTTKIF11
SCHEMBL453430 0.90 SMN1; SMN2 (0.44) SMN1; SMN2SMYD2CYP3A4HTTKIF11
SCHEMBL29368838 0.85 SMYD2 (0.37) SMN1; SMN2SMYD2CYP3A4HTTKDM4E
SCHEMBL18069583 0.85 SMYD2 (0.37) SMN1; SMN2SMYD2CYP3A4HTTKDM4E
SCHEMBL5727505 0.85 SMN1; SMN2 (0.41) SMN1; SMN2SMYD2CYP3A4HTTKIF11
SCHEMBL14059104 0.84 SMN1; SMN2 (0.37) SMN1; SMN2SMYD2CYP3A4HTTRAB9A
SCHEMBL3412361 0.84 SMYD2 (0.37) SMN1; SMN2SMYD2CYP3A4HTT
SCHEMBL3415813 0.84 SMYD2 (0.37) SMN1; SMN2SMYD2CYP3A4HTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2025242903-A1 COMPOUNDS AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR THE TREATMENT OF PROLIFERATIVE DISEASES ONCO3R THERAPEUTICS BV (BE) 2025-11-27 WO disclosed
CN-116194084-A Cleavable lipid compounds, compositions containing the same and uses thereof 赛诺菲巴斯德有限公司 2023-05-30 CN disclosed
EP-4182296-A1 CLEAVABLE LIPIDIC COMPOUNDS, COMPOSITIONS CONTAINING THEREOF, AND USES THEREOF Sanofi Pasteur (FR) 2023-05-24 EP disclosed