Enbucrilate

Enbucrilate

SCHEMBL29026258

C=C(C#N)C(=O)OCCCC.C=C(C#N)C(=O)OCCCCCCCCC

nearest known ligand 0.61

Full drug profile on Sugi Atlas →

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
TSHR P16473 5/20 0.61
ALDH1A1 P00352 3/20 0.59
NAAA Q02083 1/20 0.47
RAD52 P43351 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45
EPHX1 P07099 1/20 0.44
HPGD P15428 1/20 0.42
HCAR2 Q8TDS4 1/20 0.41
FAAH O00519 1/20 0.40
LMNA P02545 1/20 0.40
ATM Q13315 1/20 0.40
ACHE P22303 5/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Enbucrilate SCHEMBL6465405 1.00 TSHR (0.61) TSHRALDH1A1NAAARAD52NPSR1
Ocrylate SCHEMBL19579379 1.00 TSHR (0.61) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL379519 0.98 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL3457991 0.98 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL15229291 0.98 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
Ocrylate SCHEMBL29891 0.98 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL973728 0.98 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL35540 0.98 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL2903638 0.98 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1
SCHEMBL719001 0.98 TSHR (0.62) TSHRALDH1A1NAAARAD52NPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-116194521-A Curable two-part adhesive composition 博斯蒂克股份公司 2023-05-30 CN disclosed